{"product_id":"0628070640119","title":"Pirut Live (Ltd) (Rmst)","description":"\u003cp\u003eAimed at \"drug discoverers\" - i.e. any scientist who is interested in neurodegenerative diseases in general, and in finding disease-modifying treatments in particular - the first edition of \u003cu\u003eNeurodegenerative Diseases: Molecular Targets and Disease-Modifying Compounds\u003c\/u\u003e will contain both a detailed, discipline-specific coverage (paragraphs on medicinal chemistry, on clinical and preclinical characterization of compounds in development, on target identification and validation, on genetic factors influencing a pathology, etc.) and a drug discovery-oriented, overall evaluation of each target (validation, druggability, existing leads, etc.). Together these will satisfy the needs of various audiences, including \u003ci\u003ein vitro\u003c\/i\u003e biologists, pharmacologists, medicinal chemists, etc.\u003c\/p\u003e\u003cp\u003e•Written to provide a comprehensive coverage of disease-modifying mechanisms and compounds against neurodegenerative diseases\u003cbr\u003e•Provides a “drug discovery” application oriented perspective, evaluating targets and candidates for their overall therapeutic potential\u003cbr\u003e•Provides discipline-specific chapters (medicinal chemistry, target validation, preclinical and clinical development\u003cbr\u003e•Provides an overview on a number of molecular mechanisms (e.g. phosphorylation, chaperon refolding, ubiquitination, autophagy, microtubule transportation, protease cleavage, etc.) with relevance for any disease area\u003cbr\u003e•Contains a more thorough description of the therapeutic relevance of ~10 specific molecular targets\u003c\/p\u003e","brand":"Music Video Dist.***","offers":[{"title":"Default Title","offer_id":50094928265456,"sku":"0628070640119","price":29.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/shop-qa.barnesandnoble.com\/products\/0628070640119","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}