{"product_id":"2940013246638","title":"Migration of Dendritic Cell Subsets and their Precursors","description":"The ability of dendritic cells (DCs) to initiate and orchestrate immune responses is a consequence of their localization within tissues and their specialized capacity for mobilization. The migration of a given DC subset is typified by a restricted capacity for recirculation, contrasting markedly with T cells. Routes of DC migration into lymph nodes differ notably for distinct DC subsets. Here, we compare the distinct migratory patterns of plasmacytoid DCs (pDCs), CD8α+ DCs, Langerhans cells, and conventional myeloid DCs and discuss how the highly regulated patterns of DC migration in vivo may affect their roles in immunity. Finally, to gain a more molecular appreciation of the specialized migratory properties of DCs, we review the signaling cascades that govern the process of DC migration.","brand":"Annual Reviews","offers":[{"title":"Default Title","offer_id":47152569417968,"sku":"2940013246638","price":9.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/2940013246638_p0.jpg?v=1763578886","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/2940013246638","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}