{"product_id":"2940013432437","title":"A Life of Adventure in Immunobiology","description":"This article outlines my early start in medicine, a late start in immunology research, and my efforts to integrate the two activities. I first describe some of the background information, excitement, and implications of the recognition of T and B cells as separate but functionally intertwined arms of the adaptive immune system. The article continues with a brief account of my colleagues' and my efforts to use the model of hematopoietic stem cell differentiation along T and B cell lines to gain a better understanding of immunodeficiency diseases and lymphoid malignancies. It concludes with the discovery of a more ancient adaptive immune system in which T-like and B-like cells in jawless vertebrates use variable lymphocyte receptors constructed with leucine-rich-repeat sequences to recognize antigens.","brand":"Annual Reviews","offers":[{"title":"Default Title","offer_id":47175641792752,"sku":"2940013432437","price":0.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/2940013432437_p0.jpg?v=1763581200","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/2940013432437","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}