{"product_id":"2940153786766","title":"Addison's Disease, A Simple Guide To The Condition, Treatment And Related Conditions","description":"\u003cp\u003eAddison Disease is a disease that is caused by the deficiency of circulating glucocorticosteroids and mineral corticoids (aldosterone) hormones as a result of disease of the adrenal glands.\u003cbr\u003eThe causes of Addison Disease are:\u003cbr\u003e1. Auto-immune disease (Type 1 PGA – Poly-glandular Autoimmune Syndrome) of the adrenals with destruction of the adrenal parenchyma\u003cbr\u003e2. Tuberculosis of the adrenal glands\u003cbr\u003e3. Adrenal tumors that may be benign or malignant\u003cbr\u003e4. Rare causes are hemorrhage, infarction, and infiltrative diseases\u003cbr\u003eThe increased pigmentation especially in areas not exposed to the sun (such as buccal mucosa and palmar creases) and loss of weight can suggest the diagnosis of Addison Disease\u003cbr\u003eThis is due to excess pituitary production of ACTH which has melanocytes producing properties.\u003cbr\u003eThere is also sparse growth of axillary and pubic hairs.\u003cbr\u003eElectrolytes especially sodium is low, potassium and urea nitrogen is high\u003cbr\u003eACTH stimulation test with impaired corticoid response is required to confirm diagnosis\u003cbr\u003ePlasma cortisol is low (\u0026lt; 3mcg\/dL) and do not rise with ACTH stimulation\u003cbr\u003eAddison crisis is treated by intravenous normal saline and hydrocortisone 100mg every eight hours\u003cbr\u003eTreatment must be done before laboratory confirmation of diagnosis because of the danger of coma\u003cbr\u003eChronic Addison disease requires replacement of glucocorticosteroids:\u003cbr\u003eHydrocortisone 30mg daily (two thirds in the morning, one third in the evening)\u003cbr\u003eCortisone acetate 37.5 mg daily or\u003cbr\u003eFludrocortisones 0.05 to 0.2 mg daily\u003cbr\u003eDHEA 50mg orally in the morning\u003cbr\u003eAdequate salt intake is important for normal fluid and electrolyte balance.\u003cbr\u003eAddison crisis patients have excellent recovery with appropriate treatment\u003cbr\u003eChronic Addison disease patients also recovered well with replacement therapy.\u003cbr\u003eCare is needed when there is trauma, infection and surgery\u003c\/p\u003e\u003cp\u003eTABLE OF CONTENT\u003cbr\u003eIntroduction\u003cbr\u003eChapter 1 Addison Disease\u003cbr\u003eChapter 2 Interesting Facts about Adrenal Fatigue\u003cbr\u003eChapter 3 Treatment of Adrenal Fatigue\u003cbr\u003eChapter 4 Adrenal Fatigue\u003cbr\u003eChapter 5 Adrenal Tumors\u003cbr\u003eChapter 6 Adrenal Crisis\u003cbr\u003eChapter 7 Cushing Syndrome\u003cbr\u003eEpilogue\u003c\/p\u003e","brand":"Kenneth Kee","offers":[{"title":"Default Title","offer_id":47082244669680,"sku":"2940153786766","price":2.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/2940153786766_p0.jpg?v=1764056889","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/2940153786766","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}