{"product_id":"2940153834559","title":"Hyper-cortisolism (Cushing Syndrome), A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions","description":"\u003cp\u003eThe exposure of the body to excess amounts of glucocorticoids steroids is the cause of the medical disorder Hyper-cortosolism (Cushing Syndrome).\u003cbr\u003eThe Hyper-cortosolism will happen when the body is exposed to high levels of the hormone cortisol and therefore the word Hyper-cortosolism is more appropriate than Cushing Syndrome.\u003cbr\u003eIt may also happen if the patient takes too much cortisol or other steroid hormones.\u003cbr\u003ePeople of all ages are affected but more are seen in females from 30 to 50 years of age.\u003cbr\u003eThe most common cause of Hyper-cortosolism is taking excess glucocorticosteroid medicine.\u003cbr\u003eThis form of Hyper-cortosolism is called exogenous Cushing syndrome\u003cbr\u003eOther people form Hyper-cortisolism because their body secretes too much cortisol.\u003cbr\u003eThe cortisol is made in the adrenal glands.\u003cbr\u003eThe causes of too much cortisol are:\u003cbr\u003e1. Cushing disease, which happens when the pituitary gland produces too much of the hormone ACTH by itself.\u003cbr\u003eACTH then activates the adrenal glands to form too much cortisol.\u003cbr\u003eA pituitary gland tumor can produce this disorder.\u003cbr\u003e2. Tumor of the adrenal gland\u003cbr\u003ea. Tumor somewhere in the body that forms corticotrophin-releasing hormone (CRH)\u003cbr\u003eb. Tumors somewhere in the body that form ACTH (ectopic Cushing syndrome)\u003cbr\u003eExposure to excess glucocorticoids leads to multiple medical problems, such as:\u003cbr\u003e1. Hypertension,\u003cbr\u003e2. Obesity,\u003cbr\u003e3. Osteoporosis,\u003cbr\u003e4. Fractures,\u003cbr\u003e5. Impaired immune function,\u003cbr\u003e6. Impaired wound healing,\u003cbr\u003e7. Glucose intolerance,\u003cbr\u003e8. Psychosis\u003cbr\u003eMost people with Hyper-cortisolism have:\u003cbr\u003e1. Round, red, full face (moon face)\u003cbr\u003e2. Slow growth rate (in children)\u003cbr\u003e3. Weight gain with fat accumulation on the trunk\u003cbr\u003eDiagnosis of Hyper-cortisolism:\u003cbr\u003e1. The typical moon face and buffalo hump can suggest the diagnosis of Hyper-cortisolism\u003cbr\u003e2. Blood sugar and white blood cell counts may be high.\u003cbr\u003e3. Potassium level may be low.\u003cbr\u003eLaboratory tests that may be done to diagnose Hyper-cortisolism and identify the cause are:\u003cbr\u003e1. Serum cortisol levels\u003cbr\u003e2. Salivary cortisol levels\u003cbr\u003e3. Dexamethasone suppression test\u003cbr\u003e4. 24-hour urine for cortisol and creatinine\u003cbr\u003e5. ACTH level\u003cbr\u003eThe treatment for exogenous Cushing syndrome is slow withdrawal of glucocorticoid.\u003cbr\u003eMedicines used in the treatment of Cushing syndrome are:\u003cbr\u003e1. Somatostatin analogs (e.g., pasireotide)\u003cbr\u003e2. Adrenal steroid inhibitors (e.g., metyrapone, ketoconazole, aminoglutethimide, mifepristone)\u003cbr\u003eSurgical option\u003cbr\u003e1. Remove a causative tumor if possible.\u003cbr\u003eThe chosen treatment for endogenous Cushing syndrome is surgical excision of the causative tumor.\u003cbr\u003eThis primary treatment for Cushing disease is trans-sphenoidal surgery and the primary treatment for adrenal tumors is adrenalectomy.\u003cbr\u003eTABLE OF CONTENT\u003cbr\u003eIntroduction\u003cbr\u003eChapter 1 Hyper-cortisolism\u003cbr\u003eChapter 2 Causes\u003cbr\u003eChapter 3 Symptoms\u003cbr\u003eChapter 4 Diagnosis\u003cbr\u003eChapter 5 Treatment\u003cbr\u003eChapter 6 Prognosis\u003cbr\u003eChapter 7 Addison Disease\u003cbr\u003eChapter 8 Adrenal Fatigue\u003cbr\u003eEpilogue\u003c\/p\u003e","brand":"Kenneth Kee","offers":[{"title":"Default Title","offer_id":47111353532656,"sku":"2940153834559","price":2.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/2940153834559_p0.jpg?v=1764056460","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/2940153834559","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}