{"product_id":"2940153917030","title":"Huntington's Chorea, A Simple Guide To The Condition, Treatment And Related Conditions","description":"\u003cp\u003eHuntington's Chorea is a progressive degenerative disease affecting basal ganglia characterized by choreiform movements and mental deterioration.\u003cbr\u003eThe cause is believed to be genetic with autosomal dominance transmission from parent to offspring with full penetrance.\u003cbr\u003eIn Huntington's Chorea, there are widespread degeneration changes with cell loss and reactive gliosis mainly in the cerebral cortex, basal ganglia and caudate nucleus.\u003cbr\u003eThere is deficiency of gamma-aminobutyric acid (GABA).\u003cbr\u003ePhysical symptoms of Huntington's disease can begin at any age from infancy to old age but usually begin between 30 and 45 years of age.\u003cbr\u003e1. Choreiform movements\u003cbr\u003e2. Emotional disturbance with mental changes\u003cbr\u003e3. Cognitive impairment\u003cbr\u003eThe diagnosis of Huntington's Chorea involve\u003cbr\u003e1. Typical history of choreiform movements, emotional and mental impairment with family history.\u003cbr\u003e2. Physical and neurological examinations for brain neurological deficit.\u003cbr\u003e3. CT scan or MRI may show selective atrophy of the caudate nucleus helping to differentiate Huntingdon's Chorea from other causes such as dementia.\u003cbr\u003eThere is no cure for Huntington's Chorea but symptomatic control of choreiform movements with haliperidol or chlorpromazine may help.\u003cbr\u003eTetrabenazine was approved in 2008 for treatment of chorea in Huntington's disease in the US.\u003cbr\u003eOther drugs that help to reduce chorea include neuroleptics and benzodiazepines.\u003cbr\u003eNewer agents, such as quetiapine, clozapine, olanzapine, and risperidone, are preferred to older agents because of the lower incidence of extrapyramidal side effects and the decreased risk for tardive syndromes.\u003cbr\u003eResults of some studies have suggested that valproic acid and clonazepam may be effective in the treatment of chorea.\u003cbr\u003ePatients with Huntington's disease may see a physical therapist for non-invasive and non-medication-based ways of managing the physical symptoms.\u003cbr\u003eTABLE OF CONTENT\u003cbr\u003eIntroduction\u003cbr\u003eChapter 1 Huntington’s Chorea\u003cbr\u003eChapter 2 More Facts of Huntington’s Chorea\u003cbr\u003eChapter 3 Treatment of Huntington’s Chorea\u003cbr\u003eChapter 4 Cerebral Palsy\u003cbr\u003eChapter 5 Parkinson's Disease\u003cbr\u003eChapter 6 Dementia\u003cbr\u003eChapter 7 Seizures\u003cbr\u003eEpilogue\u003c\/p\u003e\u003cp\u003eOde to Huntington's Chorea\u003c\/p\u003e\u003cp\u003eHuntington's Chorea is a progressive degenerative brain condition\u003cbr\u003eThe affected basal ganglia causes choreiform movements and mental deterioration\u003cbr\u003eIt is adult-onset, autosomal dominant inherited disorder\u003cbr\u003eMost adult-onset Huntingtons inherit the gene from their mothers\u003c\/p\u003e\u003cp\u003eThe juvenile Huntingtons inherit the gene from their fathers\u003cbr\u003eInheritance through the father can lead to the disease onset earlier\u003cbr\u003eThe most important symptom is the choreiform movements\u003cbr\u003eThere is usually emotional disturbance and cognitive impairment\u003c\/p\u003e\u003cp\u003eDiagnosis is from the history of chorea and poor mental abilities\u003cbr\u003eCT scan or MRI may show the caudate nucleus having selective atrophy\u003cbr\u003eThere is no cure for Huntington's Chorea\u003cbr\u003eMental impairment may finally lead to dementia\u003c\/p\u003e\u003cp\u003eTreatment is with medications to control the symptoms\u003cbr\u003ePsychotic drugs are given for psychosis and behavioral problems\u003cbr\u003eDrugs that help to reduce chorea include Tetrabenazine\u003cbr\u003eOther drugs that help include neuroleptics and benzodiazepines\u003c\/p\u003e\u003cp\u003e-An original poem by Kenneth Kee\u003c\/p\u003e","brand":"Kenneth Kee","offers":[{"title":"Default Title","offer_id":47103411749104,"sku":"2940153917030","price":2.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/2940153917030_p0.jpg?v=1764059348","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/2940153917030","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}