{"product_id":"2940154444665","title":"Mediterranean Fever, (Brucellosis) A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions","description":"\u003cp\u003eMost people have heard of Mediterranean Diet but have they heard of Mediterranean Fever?\u003cbr\u003eMediterranean fever or Brucellosis can be used as a bioterrorism weapon.\u003cbr\u003eBrucellosis is a disease produced by a group of bacteria from the genus Brucella.\u003cbr\u003eThese bacteria can cause infection in both humans and animals.\u003cbr\u003eBrucellosis often spread to people who eat contaminated food, which can be raw meat and un-pasteurized milk.\u003cbr\u003eThe bacteria can also infect through the air or contact with an open wound.\u003cbr\u003eBrucellosis is an infectious disease that happens from contact with animals carrying brucella bacteria.\u003cbr\u003eThe disease derives its names from both its course (undulant fever) and location (Mediterranean Fever, Malta fever, Crimean fever)\u003cbr\u003eBrucella bacteria can be passed to humans if they make contact with infected meat or the placenta of infected animals (cattle, goats, camels, dogs and pigs), or if the human eats or drinks un-pasteurized milk or cheese.\u003cbr\u003eMost cases are produced by the Brucellosis melitensis bacteria.\u003cbr\u003ePeople working in occupations where they often make contact with animals or meat such as slaughterhouse workers, farmers, and veterinarians are at higher risk.\u003cbr\u003eLuckily, brucellosis is seldom spread from one human to another.\u003cbr\u003eIt can be spread through breastfeeding or blood transfusion or sexual contact (rare).\u003cbr\u003eInfection is infrequent without contact with blood or tissue.\u003cbr\u003eInhalation\u003cbr\u003eSkin or mucosa contact\u003cbr\u003eConsumption of infected or contaminated food\u003cbr\u003eSymptoms are normally non-specific:\u003cbr\u003eFever\u003cbr\u003eArthralgia\u003cbr\u003eBack pain\u003cbr\u003eWeakness\u003cbr\u003eAbdominal pain\u003cbr\u003eHigh fever spikes often happen every afternoon\u003cbr\u003eFever rises and falls in waves (undulant)\u003cbr\u003eDiagnosis is defined by:\u003cbr\u003eRose Bengal test (RBT) or serum agglutination test\u003cbr\u003eIsolation of Brucella from blood, bone marrow and liver\u003cbr\u003eBlood brucellosis antigen\u003cbr\u003eTreatment:\u003cbr\u003eAntibiotics, such as doxycycline, streptomycin, gentamicin, and rifampin, are given to treat the infection and stop it from coming back.\u003cbr\u003eFrequently, the patient needs to take the drugs for 6 weeks.\u003cbr\u003eIf there are complications from brucellosis, the patient will likely need to take the drugs for a longer period.\u003cbr\u003eDoxycycline-rifampicin-aminoglycoside (triple drug regimen) and longer treatment regimes (\u0026gt;6 weeks) have the least rates of failure.\u003c\/p\u003e\u003cp\u003eOne study of the treatment of brucellar spondylitis documented that six months of triple therapy were needed to prevent recurrences.\u003cbr\u003ePregnant Women\u003cbr\u003eCo-trimoxazole has been used in pregnant women with reported success.\u003cbr\u003eChildren\u003cbr\u003eIn pediatric patients older than 12 years, doxycycline (5 mg\/kg\/day for three weeks) plus gentamicin (5 mg\/kg\/day IM for the first five days) is the advised therapy.\u003cbr\u003eFor children younger than 12 years, trimethoprim\/sulfamethoxazole (TMP-SMZ) for three weeks and a five-day course of gentamicin are most efficacious.\u003cbr\u003eAdults\u003cbr\u003eDoxycycline (100 mg PO bd for six weeks) is the most suitable monotherapy in simple infection; but relapse rates may reach 40% for monotherapy treatment.\u003cbr\u003eRifampicin (600-900 mg\/day) is typically added to doxycycline for a full six-week course.\u003cbr\u003eDoxycycline (six weeks) plus streptomycin (two or three weeks) was a more successful regimen than doxycycline plus rifampicin (six weeks).\u003cbr\u003eStreptomycin requires daily intramuscular injections and is more costly than rifampicin.\u003cbr\u003eIn patients with spondylitis or sacroiliitis, doxycycline plus streptomycin (1 g\/day IM for three weeks) was found to be more effective than the doxycycline and rifampicin combination.\u003cbr\u003eThe quinolone plus rifampicin (6 weeks) regime is somewhat better endured than doxycycline plus rifampicin but there was no difference in efficacy.\u003cbr\u003eCorticosteroids may be indicated in CNS infection.\u003cbr\u003eMost patients resolve completely if treated early.\u003cbr\u003eTABLE OF CONTENT\u003cbr\u003eIntroduction\u003cbr\u003eChapter 1 Mediterranean Fever\u003cbr\u003eChapter 2 Causes\u003cbr\u003eChapter 3 Symptoms\u003cbr\u003eChapter 4 Diagnosis\u003cbr\u003eChapter 5 Treatment\u003cbr\u003eChapter 6 Prognosis\u003cbr\u003eChapter 7 Influenza\u003cbr\u003eChapter 8 Infectious Mononucleosis\u003cbr\u003eEpilogue\u003c\/p\u003e","brand":"Kenneth Kee","offers":[{"title":"Default Title","offer_id":47103593971952,"sku":"2940154444665","price":2.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/2940154444665_p0.jpg?v=1764068147","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/2940154444665","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}