{"product_id":"9780080464749","title":"GERD: Reflux to Esophageal Adenocarcinoma","description":"Gastroesophageal Reflux Disease (GERD) is one of the most common maladies of mankind. Approximately 40% of the adult population of the USA suffers from significant heartburn and the numerous antacids advertised incessantly on national television represents a $8 billion per year drug market. The ability to control acid secretion with the increasingly effective acid-suppressive agents such as the H2 blockers (\u003ci\u003epepcid, zantac\u003c\/i\u003e) and proton pump inhibitors (\u003ci\u003enexium, prevacid\u003c\/i\u003e) has given physicians an excellent method of treating the symptoms of acid reflux.\u003cbr\u003e\u003cbr\u003eUnfortunately, this has not eradicated reflux disease. It has just changed its nature. While heartburn, ulceration and strictures have become rare, reflux-induced adenocarcinoma of the esophagus is becoming increasingly common. Adenocarcinoma of the esophagus and gastric cardia is now the most rapidly increasing cancer type in the Western world.\u003cbr\u003e\u003cbr\u003eThe increasing incidence of esophageal adenocarcinoma has created an enormous interest and stimulus for research in this area. \u003cb\u003eGERD\u003c\/b\u003e brings together a vast amount of disparate literature and presents the entire pathogenesis of reflux disease in one place. In addition to providing a new concept of how gastroesophageal reflux causes cellular changes in the esophagus, \u003cb\u003eGERD\u003c\/b\u003e also offers a complete solution to a problem that has confused physicians for over a century. Both clinical and pathological information about reflux disease and its treatment are presented. \u003cb\u003eGERD\u003c\/b\u003e is meant to be used as a comprehensive reference for gastroenterologists, esophageal surgeons, and pathologists alike.\u003cul\u003e\n\u003cli\u003eOutlines how gastroesophageal reflux causes cellular changes in the esophagus\u003c\/li\u003e\n\u003cli\u003eBrings together the pathogenesis of the disease in one source and applies it toward clinical treatment\u003c\/li\u003e\n\u003cli\u003eTom DeMeester is THE leading international expert on reflux disease; Parakrama Chandrasoma is one of the leading pathologists in the area\u003c\/li\u003e\n\u003cli\u003eBook contains approximately 350 illustrations\u003c\/li\u003e\n\u003cli\u003eAncillary web site features color illustrations: www.chandrasoma.com \u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Elsevier Science","offers":[{"title":"Default Title","offer_id":47119121449200,"sku":"9780080464749","price":112.49,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9780080464749_p0.jpg?v=1763637580","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9780080464749","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}