{"product_id":"9780080471037","title":"Protein NMR Spectroscopy: Principles and Practice","description":"\u003cp\u003e\u003ci\u003eProtein NMR Spectroscopy, Second Edition\u003c\/i\u003e combines a comprehensive theoretical treatment of NMR spectroscopy with an extensive exposition of the experimental techniques applicable to proteins and other biological macromolecules in solution.\u003c\/p\u003e \u003cp\u003eBeginning with simple theoretical models and experimental techniques, the book develops the complete repertoire of theoretical principles and experimental techniques necessary for understanding and implementing the most sophisticated NMR experiments.\u003c\/p\u003e \u003cp\u003eImportant new techniques and applications of NMR spectroscopy have emerged since the first edition of this extremely successful book was published in 1996. This updated version includes new sections describing measurement and use of residual dipolar coupling constants for structure determination, TROSY and deuterium labeling for application to large macromolecules, and experimental techniques for characterizing conformational dynamics. In addition, the treatments of instrumentation and signal acquisition, field gradients, multidimensional spectroscopy, and structure calculation are updated and enhanced.\u003c\/p\u003e \u003cp\u003eThe book is written as a graduate-level textbook and will be of interest to biochemists, chemists, biophysicists, and structural biologists who utilize NMR spectroscopy or wish to understand the latest developments in this field. \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eProvides an understanding of the theoretical principles important for biological NMR spectroscopy\u003c\/li\u003e\n\u003cli\u003eDemonstrates how to implement, optimize and troubleshoot modern multi-dimensional NMR experiments\u003c\/li\u003e\n\u003cli\u003eAllows for the capability of designing effective experimental protocols for investigations of protein structures and dynamics\u003c\/li\u003e\n\u003cli\u003eIncludes a comprehensive set of example NMR spectra of ubiquitin provides a reference for validation of experimental methods\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Elsevier Science","offers":[{"title":"Default Title","offer_id":47148532105456,"sku":"9780080471037","price":98.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9780080471037_p0.jpg?v=1763638495","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9780080471037","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}