{"product_id":"9780080582245","title":"Linkage Thermodynamics of Macromolecular Interactions","description":"This volume commemorates the 50th anniversary of the appearance in Volume 4 in 1948 of Dr. Jeffries Wyman's famous paper in which he \"laid down\" the foundations of linkage thermodynamics. Experts in this area contribute articles on the state-of-the-art of this important field and on new developments of the original theory. Among the topics covered in this volume are electrostatic contributions to molecular free energies in solution; site-specific analysis of mutational effects in proteins; allosteric transitions of the acetylcholine receptor; and deciphering the molecular code of hemoglobin allostery.","brand":"Elsevier Science","offers":[{"title":"Default Title","offer_id":47148485247216,"sku":"9780080582245","price":175.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9780080582245_p0.jpg?v=1763638576","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9780080582245","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}