{"product_id":"9780128027110","title":"Aneurysms-Osteoarthritis Syndrome: SMAD3 Gene Mutations","description":"\u003cp\u003e\u003ci\u003eAneurysms-Osteoarthritis Syndrome: SMAD3 Gene Mutations\u003c\/i\u003e is a first-of-its-kind compilation of the genetic discovery, research, and care associated with AOS. With the field of genetically triggered aortopathies growing, this important reference will compile the newest discoveries in this field, allowing cardiologists, cardio-thoracic surgeons, clinical geneticists, vascular surgeons, orthopedic surgeons, and researchers to gain the knowledge they need without having to gather the data from various sources.\u003c\/p\u003e \u003cp\u003eCoverage includes genotype and phenotype correlations, the functional role of SMAD3, and insights into the role of TGFbeta signaling in aortic disease. The book will increase knowledge about AOS, providing awareness and better patient care for this aggressive disease.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eCovers Aneurysms-Osteoarthritis Syndrome, from genetic discovery to patient care\u003c\/li\u003e\n\u003cli\u003eContains clinical management guidance on optimal cardiovascular treatments and surgery\u003c\/li\u003e\n\u003cli\u003eExplains the autosomal dominant syndromes caused by mutations in the SMAD3 gene\u003c\/li\u003e\n\u003cli\u003eIdentifies the key features of this syndrome, including arterial aneurysms and tortuosity, early onset arthritis, and mild craniofacial features\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Elsevier Science","offers":[{"title":"Default Title","offer_id":47149490340080,"sku":"9780128027110","price":150.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9780128027110_p0.jpg?v=1763639494","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9780128027110","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}