{"product_id":"9780128035993","title":"DNA Repair in Cancer Therapy: Molecular Targets and Clinical Applications","description":"\u003cp\u003e\u003ci\u003eDNA Repair and Cancer Therapy: Molecular Targets and Clinical Applications, Second Edition\u003c\/i\u003e provides a comprehensive and timely reference that focuses on the translational and clinical use of DNA repair as a target area for the development of diagnostic biomarkers and the enhancement of cancer treatment. \u003c\/p\u003e \u003cp\u003eExperts on DNA repair proteins from all areas of cancer biology research take readers from bench research to new therapeutic approaches. This book provides a detailed discussion of combination therapies, in other words, how the inhibition of repair pathways can be coupled with chemotherapy, radiation, or DNA damaging drugs. \u003c\/p\u003e \u003cp\u003eNewer areas in this edition include the role of DNA repair in chemotherapy induced peripheral neuropathy, radiation DNA damage, Fanconi anemia cross-link repair, translesion DNA polymerases, BRCA1-BRCA2 pathway for HR and synthetic lethality, and mechanisms of resistance to clinical PARP inhibitors. \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eProvides a comprehensive overview of the basic and translational research in DNA repair as a cancer therapeutic target\u003c\/li\u003e\n\u003cli\u003eIncludes timely updates from the earlier edition, including Fanconi Anemia cross-link repair, translesion DNA polymerases, chemotherapy induced peripheral neuropathy, and many other new areas within DNA repair and cancer therapy\u003c\/li\u003e\n\u003cli\u003eSaves academic, medical, and pharma researchers time by allowing them to quickly access the very latest details on DNA repair and cancer therapy\u003c\/li\u003e\n\u003cli\u003eAssists researchers and research clinicians in understanding the importance of the breakthroughs that are contributing to advances in disease-specific research\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Elsevier Science","offers":[{"title":"Default Title","offer_id":47077279138032,"sku":"9780128035993","price":160.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9780128035993_p0.jpg?v=1772804449","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9780128035993","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}