{"product_id":"9780128038727","title":"The Rewiring Brain: A Computational Approach to Structural Plasticity in the Adult Brain","description":"\u003cp\u003eThe adult brain is not as hard-wired as traditionally thought. By modifying their small- or large-scale morphology, neurons can make new synaptic connections or break existing ones (structural plasticity). Structural changes accompany memory formation and learning, and are induced by neurogenesis, neurodegeneration and brain injury such as stroke. \u003c\/p\u003e \u003cp\u003eExploring the role of structural plasticity in the brain can be greatly assisted by mathematical and computational models, as they enable us to bridge the gap between system-level dynamics and lower level cellular and molecular processes. However, most traditional neural network models have fixed neuronal morphologies and a static connectivity pattern, with plasticity merely arising from changes in the strength of existing synapses (synaptic plasticity). In \u003ci\u003eThe\u003c\/i\u003e \u003ci\u003eRewiring Brain\u003c\/i\u003e, the editors bring together for the first time contemporary modeling studies that investigate the implications of structural plasticity for brain function and pathology. Starting with an experimental background on structural plasticity in the adult brain, the book covers computational studies on homeostatic structural plasticity, the impact of structural plasticity on cognition and cortical connectivity, the interaction between synaptic and structural plasticity, neurogenesis-related structural plasticity, and structural plasticity in neurological disorders.\u003c\/p\u003e \u003cp\u003eStructural plasticity adds a whole new dimension to brain plasticity, and \u003ci\u003eThe\u003c\/i\u003e \u003ci\u003eRewiring Brain\u003c\/i\u003e shows how computational approaches may help to gain a better understanding of the full adaptive potential of the adult brain. The book is written for both computational and experimental neuroscientists. \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eReviews the current state of knowledge of structural plasticity in the adult brain\u003c\/li\u003e\n\u003cli\u003eGives a comprehensive overview of computational studies on structural plasticity\u003c\/li\u003e\n\u003cli\u003eProvides insights into the potential driving forces of structural plasticity and the functional implications of structural plasticity for learning and memory\u003c\/li\u003e\n\u003cli\u003eServes as inspiration for developing novel treatment strategies for stimulating functional repair after brain damage\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Elsevier Science","offers":[{"title":"Default Title","offer_id":47078587990256,"sku":"9780128038727","price":150.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9780128038727_p0.jpg?v=1763640913","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9780128038727","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}