{"product_id":"9780199915866","title":"Seeking Cures: Design of Therapies for Genetically Determined Diseases","description":"\u003cp\u003eProgress in molecular and cellular biology has greatly enhanced our ability to accurately diagnose diseases that are caused by gene mutations, changes in genome structures, and altered gene expression; increased emphasis is now placed on translational research and the clinical treatment of these genetically determined diseases. \u003c\/p\u003e\u003cp\u003eSeeking Cures outlines the progress and implications of science's quest to identify therapeutic targets and initiate novel treatments at the gene, RNA, protein, and physiological levels. Also considered are aspects of treatment at the cellular level (e.g., those with hematopoietic stem cells or induced pluripotent stem cells). \u003c\/p\u003e\u003cp\u003eTopics covered in this text include: \u003c\/p\u003e\u003cp\u003e· outline of the processes typical for identifying disease-modifying therapies\u003cbr\u003e· examples of newer therapeutic approaches in use or under investigation to treat lysosomal storage diseases, inborn errors of metabolism, mitochondrial functional defects, and specific monogenic diseases \u003cbr\u003e· therapeutic designs for specific complex common diseases, including Alzheimer's disease, cancer, and autism\u003c\/p\u003e\u003cp\u003eThrough these specific examples, Seeking Cures provides a glimpse at the pursuit-and future-of personalized medicine.\u003cbr\u003e\u003c\/p\u003e","brand":"Oxford University Press, USA","offers":[{"title":"Default Title","offer_id":47023102525680,"sku":"9780199915866","price":78.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9780199915866_p0.jpg?v=1763673438","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9780199915866","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}