{"product_id":"9780387493169","title":"Multiple Testing Procedures with Applications to Genomics","description":"\u003cp\u003eThis book establishes the theoretical foundations of a general methodology for multiple hypothesis testing and discusses its software implementation in R and SAS. These are applied to a range of problems in biomedical and genomic research, including identification of differentially expressed and co-expressed genes in high-throughput gene expression experiments; tests of association between gene expression measures and biological annotation metadata; sequence analysis; and genetic mapping of complex traits using single nucleotide polymorphisms. The procedures are based on a test statistics joint null distribution and provide Type I error control in testing problems involving general data generating distributions, null hypotheses, and test statistics.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e","brand":"Springer New York","offers":[{"title":"Default Title","offer_id":47020721504496,"sku":"9780387493169","price":249.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9780387493169_p0.jpg?v=1763695649","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9780387493169","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}