{"product_id":"9780896035560","title":"Lupus: Molecular and Cellular Pathogenesis","description":"Leading basic and clinical investigators from around the world summarize the most recent research on the molecular and cellular origins of lupus. Their cutting-edge articles review the mechanisms underlying abnormal immunity and introduce the powerful new concept that a disorder of multiple genes underlies the abnormal immune response, leading directly to the development of lupus. This pathophysiology is shown to involve a wide variety of cell types, including T cells, B cells, natural killer cells, macrophages\/monocytes, and endothelial cells. Over time, the resulting long-term inflammation causes irreversible cell destruction and, ultimately, organ failure. Lupus: Molecular and Cellular Pathogenesis is a masterful new synthesis of all the new knowledge emerging today about lupus. Its new perspectives will sharpen the focus of research and ultimately lead to better and more effective treatment.","brand":"Springer-Verlag New York, LLC","offers":[{"title":"Default Title","offer_id":47033181307120,"sku":"9780896035560","price":329.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9780896035560_p0.jpg?v=1763853901","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9780896035560","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}