{"product_id":"9781118354322","title":"Biopharmaceutics Modeling and Simulations: Theory, Practice, Methods, and Applications","description":"\u003cp\u003e\u003cb\u003eA comprehensive introduction to using modeling and simulation programs in drug discovery and development\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eBiopharmaceutical modeling has become integral to the design and development of new drugs. Influencing key aspects of the development process, including drug substance design, formulation design, and toxicological exposure assessment, biopharmaceutical modeling is now seen as the linchpin to a drug's future success. And while there are a number of commercially available software programs for drug modeling, there has not been a single resource guiding pharmaceutical professionals to the actual tools and practices needed to design and test safe drugs.\u003c\/p\u003e \u003cp\u003eA guide to the basics of modeling and simulation programs, \u003ci\u003eBiopharmaceutics Modeling and Simulations\u003c\/i\u003e offers pharmaceutical scientists the keys to understanding how they work and are applied in creating drugs with desired medicinal properties. Beginning with a focus on the oral absorption of drugs, the book discusses:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eThe central dogma of oral drug absorption (the interplay of dissolution, solubility, and permeability of a drug), which forms the basis of the biopharmaceutical classification system (BCS)\u003c\/li\u003e \u003cli\u003eThe concept of drug concentration\u003c\/li\u003e \u003cli\u003eHow to simulate key drug absorption processes\u003c\/li\u003e \u003cli\u003eThe physiological and drug property data used for biopharmaceutical modeling\u003c\/li\u003e \u003cli\u003eReliable practices for reporting results\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eWith over 200 figures and illustrations and a peerless examination of all the key aspects of drug research—including running and interpreting models, validation, and compound and formulation selection—this reference seamlessly brings together the proven practical approaches essential to developing the safe and effective medicines of tomorrow.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47136101400816,"sku":"9781118354322","price":137.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9781118354322_p0.jpg?v=1763694069","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9781118354322","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}