{"product_id":"9781118618141","title":"Diversity-Oriented Synthesis: Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology","description":"\u003cp\u003e\u003cb\u003eDiscover an enhanced synthetic approach to developing and screening chemical compound libraries\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eDiversity-oriented synthesis is a new paradigm for developing large collections of structurally diverse small molecules as probes to investigate biological pathways. This book presents the most effective methods in diversity-oriented synthesis for creating small molecule collections. It offers tested and proven strategies for developing diversity-oriented synthetic libraries and screening methods for identifying ligands. Lastly, it explores some promising new applications based on diversity-oriented synthesis that have the potential to dramatically advance studies in drug discovery and chemical biology.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eDiversity-Oriented Synthesis\u003c\/i\u003e begins with an introductory chapter that explores the basics, including a discussion of the relationship between diversity-oriented synthesis and classic combinatorial chemistry. Divided into four parts, the book:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eOffers key chemical methods for the generation of small molecules using diversity-oriented principles, including peptidomimetics and macrocycles\u003c\/li\u003e \u003cli\u003eExpands on the concept of diversity-oriented synthesis by describing chemical libraries\u003c\/li\u003e \u003cli\u003eProvides modern approaches to screening diversity-oriented synthetic libraries, including high-throughput and high-content screening, small molecule microarrays, and smart screening assays\u003c\/li\u003e \u003cli\u003ePresents the applications of diversity-oriented synthetic libraries and small molecules in drug discovery and chemical biology, reporting the results of key studies and forecasting the role of diversity-oriented synthesis in future biomedical research\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eThis book has been written and edited by leading international experts in organic synthesis and its applications. Their contributions are based on a thorough review of the current literature as well as their own firsthand experience developing synthetic methods and applications.\u003c\/p\u003e \u003cp\u003eClearly written and extensively referenced, \u003ci\u003eDiversity-Oriented Synthesis\u003c\/i\u003e introduces novices to this highly promising field of research and serves as a springboard for experts to advance their own research studies and develop new applications.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47130369065200,"sku":"9781118618141","price":160.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9781118618141_p0.jpg?v=1763694704","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9781118618141","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}