{"product_id":"9781118671351","title":"Handbook of LC-MS Bioanalysis: Best Practices, Experimental Protocols, and Regulations","description":"\u003cp\u003e\u003cb\u003eConsolidates the information LC-MS bioanalytical scientists need to analyze small molecules and macromolecules\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eThe field of bioanalysis has advanced rapidly, propelled by new approaches for developing bioanalytical methods, new liquid chromatographic (LC) techniques, and new mass spectrometric (MS) instruments. Moreover, there are a host of guidelines and regulations designed to ensure the quality of bioanalytical results.\u003c\/p\u003e \u003cp\u003ePresenting the best practices, experimental protocols, and the latest understanding of regulations, this book offers a comprehensive review of LC-MS bioanalysis of small molecules and macromolecules. It not only addresses the needs of bioanalytical scientists working on routine projects, but also explores advanced and emerging technologies such as high-resolution mass spectrometry and dried blood spot microsampling.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eHandbook of LC-MS Bioanalysis\u003c\/i\u003e features contributions from an international team of leading bioanalytical scientists. Their contributions reflect a review of the latest findings, practices, and regulations as well as their own firsthand analytical laboratory experience. The book thoroughly examines:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eFundamentals of LC-MS bioanalysis in drug discovery, drug development, and therapeutic drug monitoring\u003c\/li\u003e \u003cli\u003eThe current understanding of regulations governing LC-MS bioanalysis\u003c\/li\u003e \u003cli\u003eBest practices and detailed technical instructions for LC-MS bioanalysis method development, validation, and stability assessment of analyte(s) of interest\u003c\/li\u003e \u003cli\u003eExperimental guidelines and protocols for quantitative LC-MS bioanalysis of challenging molecules, including pro-drugs, acyl glucuronides, N-oxides, reactive compounds, and photosensitive and autooxidative compounds\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eWith its focus on current bioanalytical practice, \u003ci\u003eHandbook of LC-MS Bioanalysis\u003c\/i\u003e enables bioanalytical scientists to develop and validate robust LC-MS assay methods, all in compliance with current regulations and standards.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47121646780656,"sku":"9781118671351","price":159.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9781118671351_p0.jpg?v=1763694933","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9781118671351","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}