{"product_id":"9781119990277","title":"Label-Free Technologies For Drug Discovery","description":"Over the past two decades the benefits of label-free biosensor analysis have begun to make an impact in the market, and systems are beginning to be used as mainstream research tools in many drug discovery laboratories. \u003cp\u003e\u003ci\u003eLabel-Free Technologies For Drug Discovery\u003c\/i\u003e summarises the latest and emerging developments in label-free detection systems, their underlying technology principles and end-user case studies that reveal the power and limitations of label-free in all areas of drug discovery.\u003c\/p\u003e \u003cp\u003eLabel-free technologies discussed include SPR, NMR, high-throughput mass spectrometry, resonant waveguide plate-based screening, transmitted-light imaging, isothermal titration calorimetry, optical and impedance cell-based assays and other biophysical methods. The technologies are discussed in relation to their use as screening technologies, high-content technologies, hit finding and hit validation strategies, mode of action and ADME\/T, access to difficult target classes, cell-based receptor\/ligand interactions particularly orphan receptors, and antibody and small molecule affinity and kinetic analysis.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eLabel-Free Technologies For Drug Discovery\u003c\/i\u003e is an essential guide to this emerging class of tools for researchers in drug discovery and development, particularly high-throughput screening and compound profiling teams, medicinal chemists, structural biologists, assay developers, ADME\/T specialists, and others interested in biomolecular interaction analysis.\u003c\/p\u003e","brand":"Wiley","offers":[{"title":"Default Title","offer_id":47107350823152,"sku":"9781119990277","price":182.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9781119990277_p0.jpg?v=1769890805","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9781119990277","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}