{"product_id":"9781461447559","title":"Sodium Calcium Exchange: A Growing Spectrum of Pathophysiological Implications: Proceedings of the 6th International Conference on Sodium Calcium Exchange","description":"\u003cp\u003eThis book reports the text of the lectures of the 6\u003csup\u003eth\u003c\/sup\u003e International Conference on Sodium Calcium Exchange held in Lacco Ameno in the Island of Ischia in the Gulf of Naples, Italy, from October 1 to October 5, 2011. \u003c\/p\u003e\u003cp\u003eThe present book uncovers the most striking new findings on NCX that emerged since the previous Conference on Sodium Calcium Exchange, such as the structural dissection of the molecular determinants of Ca\u003csup\u003e2+\u003c\/sup\u003e sensitivity of the exchanger, the epigenetic regulation of \u003ci\u003encx1\u003c\/i\u003e gene, the molecular identification of the mihondrial Sodium Calcium Exchanger, and the discovery of NCX in unexpected anatomical locations such as the female reproductive tract.\u003c\/p\u003e\u003cp\u003eThe book is organized into 11 parts covering NCX structural aspects, genetic and epigenetic regulation, regulatory mechanisms, subcellular localization in mihondria, involvement in neurodegenerative diseases and in immune regulation, and the role of the cardiovascular and endocrine systems, as well as diabetes in physiology and pathophysiology. Selected chapters of the book are also devoted to the interaction of NCKX and other ion channels and transporters with NCX, like ASICs, TRPM, and NHE. \u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e","brand":"Springer US","offers":[{"title":"Default Title","offer_id":47053775438064,"sku":"9781461447559","price":169.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9781461447559_p0.jpg?v=1765233224","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9781461447559","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}