{"product_id":"9781475756869","title":"Lupus: Molecular and Cellular Pathogenesis","description":"\u003cp\u003eLeading basic and clinical investigators from around the world summarize the most recent research on the molecular and cellular origins of lupus. Their cutting-edge articles review the mechanisms underlying abnormal immunity and introduce the powerful new concept that a disorder of multiple genes underlies the abnormal immune response, leading directly to the development of lupus. This pathophysiology is shown to involve a wide variety of cell types, including T cells, B cells, natural killer cells, macrophages\/monocytes, and endothelial cells. Over time, the resulting long-term inflammation causes irreversible cell destruction and, ultimately, organ failure. Lupus: Molecular and Cellular Pathogenesis is a masterful new synthesis of all the new knowledge emerging today about lupus. Its new perspectives will sharpen the focus of research and ultimately lead to better and more effective treatment.\u003c\/p\u003e","brand":"Springer-Verlag New York, LLC","offers":[{"title":"Default Title","offer_id":47031866491120,"sku":"9781475756869","price":229.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9781475756869_p0.jpg?v=1763605300","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9781475756869","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}