{"product_id":"9781848163386","title":"Protein-protein Complexes: Analysis, Modeling And Drug Design","description":"Given the immense progress achieved in elucidating protein-protein complex structures and in the field of protein interaction modeling, there is great demand for a book that gives interested researchers\/students a comprehensive overview of the field. This book does just that. It focuses on what can be learned about protein-protein interactions from the analysis of protein-protein complex structures and interfaces. What are the driving forces for protein-protein association? How can we extract the mechanism of specific recognition from studying protein-protein interfaces? How can this knowledge be used to predict and design protein-protein interactions (interaction regions and complex structures)? What methods are currently employed to design protein-protein interactions, and how can we influence protein-protein interactions by mutagenesis and small-molecule drugs or peptide mimetics?The book consists of about 15 review chapters, written by experts, on the characterization of protein-protein interfaces, structure determination of protein complexes (by NMR and X-ray), theory of protein-protein binding, dynamics of protein interfaces, bioinformatics methods to predict interaction regions, and prediction of protein-protein complex structures (docking and homology modeling of complexes, etc.) and design of protein-protein interactions. It serves as a bridge between studying\/analyzing protein-protein complex structures (interfaces), predicting interactions, and influencing\/designing interactions.","brand":"Imperial College Press","offers":[{"title":"Default Title","offer_id":47057832313072,"sku":"9781848163386","price":141.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9781848163386_p0.jpg?v=1763750211","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9781848163386","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}