{"product_id":"9783038423768","title":"Recent Advances in HTLV Research 2015","description":"\u003cp\u003eThe human T-cell leukemia virus types 1 and 2 (HTLV-1 and HTLV-2) were both discovered over three decades ago and infect millions people worldwide. HTLV-1 is associated with the adult T-cell leukemia\/lymphoma (ATLL) in about 2% of individuals infected, and another 2 to 3% of individuals develop a neurologic disorder called HTLV-associated myelopathy (HAM). HTLV-2 causes HAM in approximately 1 to 2% of infected individuals, but does not cause ATLL. HTLV-1 and HTLV-2 have served as excellent models for the study of the epidemiology and pathogenesis of virus-associated cancers as well as autoimmune conditions such as multiple sclerosis. Recently, two new members—HTLV-3 and HTLV-4—have been discovered in bushmeat hunters from central Africa, which emphasizes the urgent need for continual surveillance for new human retroviruses and their capacity to cause disease.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eImportant public health issues remain open issues to be addressed in spite of the basic epidemiology of HTLV-1 and HTLV-2 being reasonably well defined. Clinical research is needed in developing potential HTLV-1 and HTLV-2 vaccines, as well as development of treatment options for ATLL and HAM. This ‘Recent Advances Issue’ contains both reviews and updates on research that encompasses these areas.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e","brand":"MDPI AG","offers":[{"title":"Default Title","offer_id":47044716232944,"sku":"9783038423768","price":40.5,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9783038423768_p0.jpg?v=1763717053","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9783038423768","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}