{"product_id":"9783639252194","title":"Clinical Pharmacology","description":"This study was designed to compare the pharmacokinetic parameters of Metronidazole in healthy volunteers and in human patients suffering from amebiasis\u003cbr\u003e (by confirming after Stool test). It was conducted in six healthy male volunteers and six male patients suffering from amoebiasis in Services Institute of Medical Sciences (SIMS),\u003cbr\u003e Lahore, Pakistan, all individuals were between the ages of\u003cbr\u003e 25-40 years. Both groups were treated with Metronidazole\u003cbr\u003e 500mg orally per individual. Blood samples were collected at\u003cbr\u003e 0, 0.25, 0.5, 1, 2, 3, 6, 12, 24 \u0026amp; 36 hrs after oral administration of Metronidazole. Metronidazole concentrations in the plasma were measured by High\u003cbr\u003e Performance Liquid Chromatographic (HPLC) method.\u003cbr\u003e Pharmacokinetics parameters were calculated from plasma concentration- time profile data. Pharmacokinetics of\u003cbr\u003e Metronidazole in healthy volunteers and in patients with amebiasis which compared. Data was analyzed by statistical methods (T-test) and it was observed that there was no significant difference in pharmacokinetic parameters of metronidazole in healthy volunteers and in amoebiasis patients after oral administration found.","brand":"VDM Verlag Dr. Mueller AG \u0026 Co. Kg","offers":[{"title":"Default Title","offer_id":47041757741296,"sku":"9783639252194","price":65.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9783639252194_p0.jpg?v=1763727745","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9783639252194","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}