{"product_id":"9783642761911","title":"Rheumatoid Arthritis: Recent Research Advances","description":"Many advances have occurred in the last 5 years especially in understanding genetic susceptibility factors, the role of immune response in chronic arthritis and the relationship between cellular processes that underlie inflammation and tissue damage. All these are dealt with in depth in the individual contributions.\u003cbr\u003eGenetics studies included illustrate how studies of HLA\u003cbr\u003egenes and genes controlling the autoantibody repertoire may be involved. Environmental factors are believed to be important and studies both in humans and in experimental models on the role of viral and bacterial agents are covered. The fascinating relationship between microbes,\u003cbr\u003edysregulated immune responses and oncogenes are also examined.\u003cbr\u003eSince autoimmunity is the key aspect of the immunological response in rheumatoid arthritis, the role of antigens is re-examined as is the part played by immune T and B cells.\u003cbr\u003eNew areas of clinical application of basic science is well presented in this book, forexample, in examining how markers of cartilage destruction may become important in monitoring disease activity. A chapter reviewing possible future novel therapies is included.","brand":"Springer Berlin Heidelberg","offers":[{"title":"Default Title","offer_id":47036829630704,"sku":"9783642761911","price":139.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9783642761911_p0.jpg?v=1763727866","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9783642761911","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}