{"product_id":"9784431669166","title":"Neocarzinostatin: The Past, Present, and Future of Anticancer Drug","description":"The 20th century has witnessed the great benefits of the development of antibi­ otics, which became a reality after World War IL More than 50 years ago I witnessed the miraculous therapeutic power of penicillin, when I was a student at the Tohoku University Medical School's Department of Bacteriology in Sendai, Japan. The late Dr. Kondo was a graduate student in the department at that time and developed the first crude penicillin preparation in Japan which was applied with dramatic results in two patients. Although there was patient-family consent at that time, ethics committees, randomization. mutagenesis tests, distribution studies, purity-criteria, and phar­ macokinetics were not yet in existence. Today, regulatory procedures have com­ plicated the whole drug-approval process. For example, any new antibiotics that have been proven effective in laboratory studies against gram-negative bacteria, as might exist in deadly plague bacteria, must still undergo a long and enormously costly regulatory process before they can be introduced to benefit society, and before government insurance can be applied.","brand":"Springer Japan","offers":[{"title":"Default Title","offer_id":47055961522416,"sku":"9784431669166","price":139.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9784431669166_p0.jpg?v=1763713633","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9784431669166","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}