{"product_id":"9789814397445","title":"Handbook Of Immunological Properties Of Engineered Nanomaterials","description":"\u003cp\u003eThe \u003ci\u003eHandbook of Immunological Properties of Engineered Nanomaterials\u003c\/i\u003e provides a comprehensive overview of the current literature, methodologies, and translational and regulatory considerations in the field of nanoimmunotoxicology. The main subject is the immunological properties of engineered nanomaterials. Focus areas include interactions between engineered nanomaterials and red blood cells, platelets, endothelial cells, professional phagocytes, T cells, B cells, dendritic cells, complement and coagulation systems, and plasma proteins, with discussions on nanoparticle sterility and sterilization. Each chapter presents a broad literature review of the given focus area, describes protocols and resources available to support research in the individual focus areas, highlights challenges, and outlines  unanswered questions and future directions. In addition, the Handbook includes an overview of and serves a guide to the physicochemical characterization of engineered nanomaterials essential to conducting meaningful immunological studies of nanoparticles. Regulations related to immunotoxicity testing of materials prior to their translation into the clinic are also reviewed.\u003c\/p\u003e\u003cp\u003eThe Handbook is written by top experts in the field of nanomedicine, nanotechnology, and translational bionanotechnology, representing academia, government, industry, and consulting organizations, and regulatory agencies. The Handbook is designed to serve as a textbook for students, a practical guide for research laboratories, and an informational resource for scientific consultants, reviewers, and policy makers. It is written such that both experts and beginners will find the information highly useful and applicable.\u003c\/p\u003e\u003cb\u003eContents:\u003c\/b\u003e\u003cul\u003e\n\u003cli\u003eImmunological Properties of Engineered Nanomaterials: An Introduction \u003ci\u003e(Marina A Dobrovolskaia and Scott E McNeil)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eImportance of Physicochemical Characterization Prior to Immunological Studies \u003ci\u003e(Jeffrey D Clogston and Anil K Patri)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eImpact of Nanoparticle Sterilization on Analytical Characterization \u003ci\u003e(Nanda Subbarao)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eEndotoxin and Engineered Nanomaterials \u003ci\u003e(Marina A Dobrovolskaia and Scott E McNeil)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eSurface Adsorbates on Nanomaterials and Their Possible Roles in Host Inflammatory and Toxicological Processing \u003ci\u003e(Clinton F Jones, David G Castner, and David W Grainger)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eNanoparticle Interaction with Plasma Proteins as It Relates to Biodistribution \u003ci\u003e(Lennart Treuel and G Ulrich Nienhaus)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eThe Effects of Engineered Nanomaterials on Erythrocytes \u003ci\u003e(Bridget Wildt, Richard A Malinauskas, and Ronald P Brown)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eThe Effects of Engineered Nanomaterials on Cultured Endothelial Cells \u003ci\u003e(Jan Simak)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eThe Effect of Engineered Nanomaterials on the Plasma Coagulation System \u003ci\u003e(Jan Simak)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eThe Effects of Engineered Nanomaterials on Platelets \u003ci\u003e(Jan Simak)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eComplement Activation \u003ci\u003e(Carolina Salvador-Morales and Robert B Sim)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eBidirectional Interaction Between Nanoparticles and Cells of the Mononuclear Phagocytic System \u003ci\u003e(Whitney P Caron, Sumit Rawal, Gina Song, Parag Kumar, John C Lay, and William C Zamboni)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eThe Effects of Nanoparticles on Dendritic Cells \u003ci\u003e(Valentyna Fesenkova)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eThe Effects of Nanoparticles on Bone Marrow Cells \u003ci\u003e(Ekaterina Dadachova)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eNanoparticles, Immunomodulation and Vaccine Delivery \u003ci\u003e(Sue D Xiang, Martina Fuchsberger, Tanya De L Karlson, Charles L Hardy, Cordelia Selomulya and Magdalena Plebanski)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eNanoparticles as Drug Delivery Vehicles for the Therapy of Inflammatory Disorders \u003ci\u003e(Deepthy Menon, J Gopikrishna, Dhanya Narayanan, and Shantikumar V Nair)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eNanostructures and Allergy \u003ci\u003e(Silvia Lorenzo-Abalde and África González-Fernández)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eNanoparticles and Antigenicity \u003ci\u003e(Marina A Dobrovolskaia)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci\u003eIn Vitro\u003c\/i\u003e Assays for Monitoring Nanoparticle Interaction with Components of the Immune System \u003ci\u003e(Marina A Dobrovolskaia and Scott E McNeil)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eEvaluating the Adverse Effects of Nanomaterials on the Immune System with Animal Models \u003ci\u003e(Matthew J Smith, Colleen E McLoughlin, Kimber L White, Jr, and Dori R Germolec)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eImmunotoxicity Testing for Drug–Nanoparticle Conjugates: Regulatory Considerations \u003ci\u003e(Simona Bancos, Katherine M Tyner, and James L Weaver)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\u003cbr\u003e\u003cb\u003eReadership:\u003c\/b\u003e Researchers, academics, undergraduates and graduates in toxicology, immunotoxicology and nanomedicine, and industry (small and mid biotech companies and big pharmaceutical companies), as well as regulatory agencies (EPA, FDA) and physicians.\u003cbr\u003e","brand":"World Scientific Publishing Company, Incorporated","offers":[{"title":"Default Title","offer_id":47185220829424,"sku":"9789814397445","price":75.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9789814397445_p0.jpg?v=1763691410","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9789814397445","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}