{"product_id":"9789814566384","title":"Dynamics Of Cancer: Mathematical Foundations Of Oncology: Mathematical Foundations of Oncology","description":"\u003cp\u003eThe book aims to provide an introduction to mathematical models that describe the dynamics of tumor growth and the evolution of tumor cells. It can be used as a textbook for advanced undergraduate or graduate courses, and also serves as a reference book for researchers. The book has a strong evolutionary component and reflects the viewpoint that cancer can be understood rationally through a combination of mathematical and biological tools. It can be used both by mathematicians and biologists. Mathematically, the book starts with relatively simple ordinary differential equation models, and subsequently explores more complex stochastic and spatial models. Biologically, the book starts with explorations of the basic dynamics of tumor growth, including competitive interactions among cells, and subsequently moves on to the evolutionary dynamics of cancer cells, including scenarios of cancer initiation, progression, and treatment. The book finishes with a discussion of advanced topics, which describe how some of the mathematical concepts can be used to gain insights into a variety of questions, such as epigenetics, telomeres, gene therapy, and social interactions of cancer cells.\u003c\/p\u003e\u003cb\u003eContents:\u003c\/b\u003e\u003cul\u003e\n\u003cul\u003e\n\u003cli\u003eTeaching Guide\u003c\/li\u003e\n\u003cli\u003eCancer and Somatic Evolution\u003c\/li\u003e\n\u003cli\u003eMathematical Modeling of Tumorigenesis\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003e\n\u003cb\u003e\u003ci\u003eBasic Growth Dynamics and Deterministic Models:\u003c\/i\u003e\u003c\/b\u003e\u003cul\u003e\n\u003cli\u003eSingle Species Growth\u003c\/li\u003e\n\u003cli\u003eTwo-Species Competition Dynamics\u003c\/li\u003e\n\u003cli\u003eCompetition Between Genetically Stable and Unstable Cells\u003c\/li\u003e\n\u003cli\u003eChromosomal Instability and Tumor Growth\u003c\/li\u003e\n\u003cli\u003eAngiogenesis Inhibitors, Promoters, and Spatial Growth\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003e\u003ci\u003eEvolutionary Dynamics and Stochastic Models:\u003c\/i\u003e\u003c\/b\u003e\u003cul\u003e\n\u003cli\u003eEvolutionary Dynamics of Tumor Initiation Through Oncogenes: The Gain-of-Function Model\u003c\/li\u003e\n\u003cli\u003eEvolutionary Dynamics of Tumor Initiation Through Tumor-Suppressor Genes: The Loss-of-Function Model and Stochastic Tunneling\u003c\/li\u003e\n\u003cli\u003eMicrosatellite and Chromosomal Instability in Sporadic and Familial Colorectal Cancers\u003c\/li\u003e\n\u003cli\u003eEvolutionary Dynamics in Hierarchical Populations\u003c\/li\u003e\n\u003cli\u003eSpatial Evolutionary Dynamics of Tumor Initiation\u003c\/li\u003e\n\u003cli\u003eComplex Tumor Dynamics in Space\u003c\/li\u003e\n\u003cli\u003eStochastic Modeling of Cellular Growth, Treatment, and Resistance Generation\u003c\/li\u003e\n\u003cli\u003eEvolutionary Dynamics of Drug Resistance in Chronic Myeloid Leukemia\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003e\u003ci\u003eAdvanced Topics:\u003c\/i\u003e\u003c\/b\u003e\u003cul\u003e\n\u003cli\u003eEvolutionary Dynamics of Stem-Cell Driven Tumor Growth\u003c\/li\u003e\n\u003cli\u003eTumor Growth Kinetics and Disease Progression\u003c\/li\u003e\n\u003cli\u003eEpigenetic Changes and the Rate of DNA Methylation\u003c\/li\u003e\n\u003cli\u003eTelomeres and Cancer Protection\u003c\/li\u003e\n\u003cli\u003eGene Therapy and Oncolytic Virus Therapy\u003c\/li\u003e\n\u003cli\u003eImmune Responses,  Tumor Growth, and Therapies\u003c\/li\u003e\n\u003cli\u003eTowards Higher Complexities: Social Interactions\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\u003cbr\u003e\u003cb\u003eReadership:\u003c\/b\u003e Researchers in mathematical biology, mathematical modeling, biology, mathematical oncology.\u003cbr\u003e","brand":"World Scientific Publishing Company, Incorporated","offers":[{"title":"Default Title","offer_id":47141187289328,"sku":"9789814566384","price":59.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9789814566384_p0.jpg?v=1763691237","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9789814566384","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}