{"product_id":"9789814602174","title":"Frontiers In Autism Research: New Horizons For Diagnosis And Treatment: New Horizons for Diagnosis and Treatment","description":"\u003cp\u003eThis book focuses on the emerging and expanding areas of research on ASD and their potential to lead to better diagnosis and more effective therapies. These areas include innovative and integrative approaches to genetic\/genomic analyses and investigations of epigenetic contributions, including the role of noncoding RNAs, DNA methylation, alternative splicing, RNA editing, and faulty translation in gene regulation and expression, metabolic and immune dysfunction, co-morbidities, as well as hormonal and gene-environment interactions that may increase risk for ASD.\u003c\/p\u003e\u003cp\u003eWithin each chapter, experts review cutting-edge research as well as provide their perspective on the future of research in their respective areas, including the challenges involved and the types of studies or advances that are necessary to move the field forward to achieve predicted translational goals.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eContributors:\u003c\/b\u003e Argel Aguilar-Valles, Evdokia Anagnostou, Emma Ashwin, Bonnie Auyeung, Kelly M Bakulski, Simon Baron-Cohen, Margaret L Bauman, Donna Betts, Chad A Bousman, Daniel B Campbell, Manuel F Casanova, Bhismadev Chakrabarti, Gursharan Chana, Abha Chauhan, Ved Chauhan, Jessica DeWitt, Keith W Dunaway, Alal Eran, Ian P Everall, M Daniele Fallin, Richard E Frye, Piers Gillett, Matthew Ginsberg, Christos G Gkogkas, Rhonda J Greenhaw, Simon G Gregory, Elena L Grigorenko, Feng Gu, Rebecca Harmer, Martha Herbert, Valerie W Hu, Karen L Jones, Petra Kern, Arkady Khoutorsky, Rebecca Knickmeyer, Isaac S Kohane, Louis M Kunkel, Janine M LaSalle, Michael V Lombardo, Deepali Mankad, Marvin Natowicz, Laura Nicholls, Christos Pantelis, Natalia Rakhlin, Radhika Ramadas, Daniel A Rossignol, Tewarit Sarachana, Stephen W Scherer, Gabriela Schmulevich, Ayten Shah, Frank R Sharp, Alison B Singer, Efstratios Skafidas, Estate M Sokhadze, Nahum Sonenberg, Boryana Stamova, Zohreh Talebizadeh, Renee Testa, Judy Van de Water, Irina Voineagu, Daniel Williams, Ryan K C Yuen, Daniela Zantomio.\u003c\/p\u003e\u003cb\u003eContents:\u003c\/b\u003e\u003cul\u003e\n\u003cb\u003e\u003ci\u003eDissecting the Genetic Architecture of ASD:\u003c\/i\u003e\u003c\/b\u003e\u003cul\u003e\n\u003cli\u003ePhenotype Definition: A Cornerstone of Autism Research, Diagnosis and Therapy \u003ci\u003e(Valerie W Hu)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eFrom Molecular Pathways to ASD Therapy: Insights from Syndromic Forms of Autism \u003ci\u003e(Laura Nicholls, Radhika Ramadas and Irina Voineagu)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eLanguage Impairment in Autism Spectrum Disorders \u003ci\u003e(Natalia Rakhlin and Elena L Grigorenko)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eWhole Genome Sequencing in Autism: Clinical Translation \u003ci\u003e(Ryan K C  Yuen and Stephen W Scherer)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eThe Impact of Integrative Unconventional Data Analysis Approaches on Advancing Autism Genetics Research \u003ci\u003e(Zohreh Talebizadeh and Ayten Shah)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eConstruction of a Genetic Classifier for ASD Using Gene Pathway Analysis \u003ci\u003e(Gursharan Chana, Renee Testa, Piers Gillett, Daniel Williams, Chad A Bousman, Daniela Zantomio, Ian P Everall, Christos Pantelis and Efstratios Skafidas)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cb\u003e\u003ci\u003eGene Dysregulation in ASD: From Transcription to Translation:\u003c\/i\u003e\u003c\/b\u003e\u003cul\u003e\n\u003cli\u003eGenome-Wide Expression Studies of Blood and Lymphoblastoid Cell Lines in Autism Spectrum Disorders \u003ci\u003e(Boryana Stamova and Frank R Sharp)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eSearching in the “Dark”: Non-Coding RNA as a New Avenue of Autism Research \u003ci\u003e(Tewarit Sarachana and Valerie W Hu)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eTargeting Noncoding RNA for Treatment of Autism Spectrum Disorders \u003ci\u003e(Jessica DeWitt and Daniel B Campbell)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eA-to-I RNA Editing in Autism Spectrum Disorder \u003ci\u003e(Alal Eran, Isaac S Kohane and Louis M Kunkel)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eTranslational Control of Autism and Fragile-X Syndrome \u003ci\u003e(Christos G Gkogkas, Argel Aguilar-Valles, Arkady Khoutorsky and Nahum Sonenberg)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cb\u003e\u003ci\u003eEpigenetic, Environmental, and Physiological Contributions to ASD:\u003c\/i\u003e\u003c\/b\u003e\u003cul\u003e\n\u003cli\u003eEpigenetics in Autism \u003ci\u003e(Matthew Ginsberg and Marvin Natowicz)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eThe Epigenetics of Autism — Running Beyond the Bases \u003ci\u003e(Simon G Gregory)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eGenes and Environment in Autism Spectrum Disorders: An Integrated Perspective \u003ci\u003e(Kelly M Bakulski, Alison B Singer and M Daniele Fallin)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eThe Potential Brain Drain from Environmental Exposures on the Methylome and Genome Across Generations \u003ci\u003e(Janine M LaSalle and Keith W Dunaway)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eOxidative Stress and Mitochondrial Dysfunction in ASDs \u003ci\u003e(Feng Gu, Ved Chauhan and Abha Chauhan)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eMaternal Autoantibodies in Autism Spectrum Disorder \u003ci\u003e(Karen L Jones and Judy Van de Water)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eWhy is Autism More Common in Males? \u003ci\u003e(Simon Baron-Cohen, Michael V Lombardo, Bonnie Auyeung, Emma Ashwin, Bhismadev Chakrabarti and Rebecca Knickmeyer)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cb\u003e\u003ci\u003eMoving Towards Personalized Treatment of ASD and Lifespan Issues:\u003c\/i\u003e\u003c\/b\u003e\u003cul\u003e\n\u003cli\u003eFuture Directions in Psychopharmacology of Autism Spectrum Disorder \u003ci\u003e(Deepali Mankad and Evdokia Anagnostou)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eMedical Co-Morbidities in Autism: Clues to Underlying Biological Mechanisms and\/or Diagnostic Subtypes? \u003ci\u003e(Margaret L Bauman)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eTranslational Implications of a Whole-Body Approach to Brain Health in Autism: How Transduction Between Metabolism and Electrophysiology Points to Mechanisms for Neuroplasticity \u003ci\u003e(Martha R Herbert)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eAchieving Optimal Outcomes in Autism: Treating Potentially Reversible Conditions Associated with Autism Spectrum Disorder \u003ci\u003e(Richard E Frye and Daniel A Rossignol)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eTranscranial Magnetic Stimulation: Application in Autism Treatment \u003ci\u003e(Manuel F Casanova and Estate M Sokhadze)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eMusic Therapy: Personalized Interventions for Individuals with Autism Spectrum Disorder \u003ci\u003e(Petra Kern)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eThe Contributions of Art Therapy in Treatment, Assessment, and Research with People Who have Autism Spectrum Disorders \u003ci\u003e(Donna Betts, Rebecca Harmer and Gabriela Schmulevich)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eShifting Paradigms: An Examination of Our Understanding of Adult Autism \u003ci\u003e(Rhonda J Greenhaw)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/ul\u003e\u003cbr\u003e\u003cb\u003eReadership:\u003c\/b\u003e Established investigators and students engaged in autism research; also the general population, especially families of individuals affected by ASD and their professional caregivers.\u003cbr\u003e","brand":"World Scientific Publishing Company, Incorporated","offers":[{"title":"Default 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