{"product_id":"9789814619141","title":"Human Ageing: A Unique Experience - Implications For The Disease Concept: Implications for the Disease Concept","description":"\u003cp\u003e\u003ci\u003eHuman Ageing: A Unique Experience\u003c\/i\u003e explores the biology of human ageing focusing on the individual. The book begins with the premature ageing disorder Hutchinson-Gilford Progeria syndrome and spins a web of interconnected biological domains involving lamins, telomeres, alternative splicing, genetics, epigenetics, and molecular clocks. The profound influence of culture is explored since cultural inheritance and genetic inheritance are the two intertwined processes driving human evolution. An empirical framework is developed to describe human ageing at the individual level and the implications of this framework on the whole concept of diseases are discussed.\u003c\/p\u003e\u003cb\u003eContents:\u003c\/b\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003e\u003ci\u003eThe Biology of Ageing:\u003c\/i\u003e\u003c\/b\u003e\u003cul\u003e\n\u003cli\u003eLamins: Hutchinson–Gilford Progeria Syndrome\u003c\/li\u003e\n\u003cli\u003emTOR Pathway\u003c\/li\u003e\n\u003cli\u003eMolecular Clocks\u003c\/li\u003e\n\u003cli\u003eSummary and Perspectives\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003e\u003ci\u003eAgeing and Environmental Cues (Experiences):\u003c\/i\u003e\u003c\/b\u003e\u003cul\u003e\n\u003cli\u003eRegulation of Gene Expression: Epigenetics\u003c\/li\u003e\n\u003cli\u003eEnvironmental Cues: Specific Examples\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003e\u003ci\u003eDomestication:\u003c\/i\u003e\u003c\/b\u003e\u003cul\u003e\n\u003cli\u003eThe Domestication Process: The Russian Silver Fox Experiment\u003c\/li\u003e\n\u003cli\u003eThe Dog\u003c\/li\u003e\n\u003cli\u003eSummary\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003e\u003ci\u003eSocial Context and Culture:\u003c\/i\u003e\u003c\/b\u003e\u003cul\u003e\n\u003cli\u003eOverview\u003c\/li\u003e\n\u003cli\u003eAre Humans Still Evolving?\u003c\/li\u003e\n\u003cli\u003eContemporary Evolution\u003c\/li\u003e\n\u003cli\u003eSociety, Culture, and Ageing\u003c\/li\u003e\n\u003cli\u003ePerspectives\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003e\u003ci\u003ePulling the Threads Together:\u003c\/i\u003e\u003c\/b\u003e\u003cul\u003e\n\u003cli\u003eTheme: The Biology of Ageing at the Species and Indivdual Levels\u003c\/li\u003e\n\u003cli\u003eTheme: Genetic Uniqueness of Each Individual Underlies that Individual's Unique Ageing Pattern\u003c\/li\u003e\n\u003cli\u003eTheme: Ageing and an Individual's Social and Cultural Environment\u003c\/li\u003e\n\u003cli\u003eFramework for the Ageing Process\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003e\u003ci\u003eThe Disease Construct and Ageing:\u003c\/i\u003e\u003c\/b\u003e\u003cul\u003e\n\u003cli\u003eHistory of Disease Construct\u003c\/li\u003e\n\u003cli\u003ePersonalized Medicine\u003c\/li\u003e\n\u003cli\u003eDisease or Ageing?\u003c\/li\u003e\n\u003cli\u003eDisease or Ageing: Is It Simply Semantics?\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\u003cbr\u003e\u003cb\u003eReadership:\u003c\/b\u003e Gerontologists and geriatric physicians; researchers in comparative biology and physiology, genomics and epigenomics, developmental biology. Others include researchers in sociology and history of medicine.\u003cbr\u003e","brand":"World Scientific Publishing Company, Incorporated","offers":[{"title":"Default Title","offer_id":47185302749424,"sku":"9789814619141","price":53.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9789814619141_p0.jpg?v=1763691313","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9789814619141","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}