{"product_id":"9789814635356","title":"Biology And Pathogenesis Of Rhabdo- And Filoviruses","description":"\u003cp\u003eRhabdoviruses and Filoviruses are single-stranded, non-segmented, negative-strand RNA viruses, many of which cause significant morbidity and mortality in humans and animals. Certain members of these virus families have been used as excellent model systems to understand the molecular biology of replication, host responses to infections, and viral countermeasures. Rhabdoviruses have also been used as vaccine vectors as well as oncolytic agents.\u003c\/p\u003e\u003cp\u003eStudies on Filoviruses have now provided significant insights into how they enter susceptible cells, replicate and cause disease, and also how they evade the host's immune mechanisms. This book addresses the most recent findings on Rhabdovirus and Filovirus structure, replication mechanisms, host cell responses to virus infections and viral countermeasures. Chapters on emerging viruses as well as approaches for therapeutic interventions have also been included.\u003c\/p\u003e\u003cp\u003eThis book represents an authoritative text that brings together the most recent advances on the cellular and molecular biology of Rhabdo- and Filoviruses, including mechanisms of pathogenesis.\u003c\/p\u003e\u003cbr\u003e \u003cb\u003eContents:\u003c\/b\u003e\u003cul\u003e\n\u003cli\u003eOverview of Rhabdo– and Filoviruses \u003ci\u003e(Asit K Pattnaik and Michael A Whitt)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eRhabdovirus Structure \u003ci\u003e(Ming Luo)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eThe Pathway of VSV Entry into Cells \u003ci\u003e(Shem Johnson and Jean Gruenberg)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eRhabdovirus Glycoproteins \u003ci\u003e(Yves Gaudin and Michael A Whitt)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eVSV RNA Transcription and Replication \u003ci\u003e(Jacques Perrault)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eHost Cell Functions in Vesicular Stomatitis Virus Replication \u003ci\u003e(Phat X Dinh, Anshuman Das, and Asit K Pattnaik)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eCytopathogenesis of Rhabdoviruses \u003ci\u003e(Douglas S Lyles)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eAssembly and Budding of Rhabdo– and Filoviruses \u003ci\u003e(Ziying Han and Ronald N Harty)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eRhabdoviruses as Vaccine Vectors: From Initial Development to Clinical Trials \u003ci\u003e(John K Rose and David K Clarke)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eOncolytic Rhabdoviruses \u003ci\u003e(Nicole E Forbes and John C Bell)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eUse of Rhabdoviruses to Study Neural Circuitry \u003ci\u003e(Melanie Ginger, Guillaume Bony, Matthias Haberl, and Andreas Frick)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eEvolution of Rhabdo– and Filoviruses \u003ci\u003e(Isabel S Novella, John B Presloid, and R Travis Taylor)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eEmerging Rhabdoviruses \u003ci\u003e(Imke Steffen and Graham Simmons)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eRabies Virus Replication and Pathogenesis \u003ci\u003e(Andrew W Hudacek and Matthias J Schnell)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eActivation and Evasion of Innate Immune Response by Rhabdoviruses \u003ci\u003e(Karl-Klaus Conzelmann)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eRabies Virus Vaccines \u003ci\u003e(Ying Huang, Clement W Gnanadurai, and Zhen F Fu)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eFilovirus Structure and Morphogenesis \u003ci\u003e(Timothy F Booth, Daniel R Beniac, Melissa J Rabb, and Lindsey L Lamboo)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eEpidemiology and Pathogenesis of Filovirus Infections \u003ci\u003e(Logan Banadyga and Hideki Ebihara)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eFilovirus Entry into Susceptible Cells \u003ci\u003e(Rohit K Jangra, Eva Mittler, and Kartik Chandran)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eFilovirus Transcription \u0026amp; Replication \u003ci\u003e(Kristina Brauburger, Laure R Deflubé, and Elke Muhlberger)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eInnate Immune Evasion Mechanisms of Filoviruses \u003ci\u003e(Christopher F Basler, Gaya K Amarasinghe, and Daisy W Leung)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003cli\u003eVaccines and Antivirals for Filoviruses \u003ci\u003e(Chad E Mire and Thomas W Geisbe)\u003c\/i\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e \u003cbr\u003e\u003cb\u003eReadership:\u003c\/b\u003e Investigators, graduate students, and post-graduate researchers in the field of RNA virology.\u003cbr\u003e\u003cb\u003eKey Features:\u003c\/b\u003e\u003cul\u003e\n\u003cli\u003eThe book describes the most recent advances in our understanding of cellular and molecular aspects of replication and pathogenic mechanisms of these two important viral pathogens\u003c\/li\u003e\n\u003cli\u003eUnlike other existing textbooks published earlier, this book brings together several major topics of research such as replication, host response to viral replication and viral countermeasures, viral evolution and emerging viruses, viral vectors, vaccines and antivirals, etc\u003c\/li\u003e\n\u003cli\u003eThe chapters in the book are written by renowned researchers in these fields\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"World Scientific Publishing Company, Incorporated","offers":[{"title":"Default Title","offer_id":47185520034032,"sku":"9789814635356","price":40.49,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0737\/7593\/9824\/files\/9789814635356_p0.jpg?v=1763691769","url":"https:\/\/shop-qa.barnesandnoble.com\/products\/9789814635356","provider":"Barnes \u0026 Noble (DEV)","version":"1.0","type":"link"}