Commentary on Isaiah - Volume 4

Moreover, the Prophet does not describe the commencement of the period, as if it were only from the womb that God began to call him; but it is as if he had said, "Before I came out of the womb, God had determined that I should hold this office." In like manner Paul also says that he was "set apart from the womb," (Galatians 1:15,) though he had been "elected before the creation of the world." (Ephesians 1:4.) To Jeremiah also it is said, "Before thou camest out of the womb, I knew thee." (Jeremiah 1:5.) In short, the meaning is, that Christ was clothed with our flesh by the appointment of the Father, in order that he might fulfill the office of Redeemer, to which he had been appointed.