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Hratch Karamanoukian
Dr Karamanoukian's Guide to CoQ10: What You Need to Know
Dr Karamanoukian's Guide to CoQ10: What You Need to Know
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CoQ10 is also known Coenzyme Q10 and ubiquinone. It is called "ubiquinone" because CoQ10 is ubiquitous - it is found in every cell of the body - but found in the highest levels in the heart, kidney, liver and pancreas. CoQ10 is absolutely essential for the production of energy in all the cells - it functions in the "supply chain" of ATP. ATP is the key, central substance that provides cellular energy. It is also a critical anti-oxidant - and nature's original recycler! CoQ10 can regenerate itself to act as an antiodant over and over again.
Inflammation is a normal process - it is necessary for wound healing, for the immune response and to get rid of dead bacteria, viruses and cell debris. But, when inflammation goes out of control - cells, tissues and organs are damaged. Just as a forest fire can get out of control if it isn't stopped soon enough, inflammation can get out of control Now, the forest can re-grow - but it takes time and the forest does show the scars of the fire. Cells, tissues and organs can also heal, but just as it is better to control a forest fire early, it is better to stop the inflammatory process before too much damage occurs - and that is what an antioxidant can do!
There are a number of reasons why you may not have enough CoQ10 - your body may not be making enough, you could be using it up because of some disorder or certain drugs may deplete the body's stores of CoQ10. The drugs that deplete CoQ10 include statins (cholesterol lowering drugs), beta-blockers (such as propranolol and metoprolol), phenothiazines and some tricyclic antidepressants. The anti-cancer drug, adriamycin, may also deplete CoQ10. On the other hand, people using blood thinners such as warfarin should consider not taking CoQ10 because the risk of clotting may be increased. There is also evidence that environmental toxins deplete CoQ10.
A number of cardiac conditions can be treated with CoQ10. These include atherosclerosis, ischemic heart disease, aortic/mitral stenosis or insufficiency, diabetic cardiomyopathy, tetralogy of Fallot and atrial/ventricular septal defects. Other conditions where CoQ10 supplementation have proven helpful include congestive heart failure (CHF) angina, arrhythmias, mitral valve prolapse, and high blood pressure. CoQ10 has also been shown to be protective during cardiac surgery. Other disorders where CoQ10 has been used for successful treatment include diabetes, asthma, as well as AIDs, various cancers, ulcers, muscular disorders, immune system disorders and even aging!
Inflammation is a normal process - it is necessary for wound healing, for the immune response and to get rid of dead bacteria, viruses and cell debris. But, when inflammation goes out of control - cells, tissues and organs are damaged. Just as a forest fire can get out of control if it isn't stopped soon enough, inflammation can get out of control Now, the forest can re-grow - but it takes time and the forest does show the scars of the fire. Cells, tissues and organs can also heal, but just as it is better to control a forest fire early, it is better to stop the inflammatory process before too much damage occurs - and that is what an antioxidant can do!
There are a number of reasons why you may not have enough CoQ10 - your body may not be making enough, you could be using it up because of some disorder or certain drugs may deplete the body's stores of CoQ10. The drugs that deplete CoQ10 include statins (cholesterol lowering drugs), beta-blockers (such as propranolol and metoprolol), phenothiazines and some tricyclic antidepressants. The anti-cancer drug, adriamycin, may also deplete CoQ10. On the other hand, people using blood thinners such as warfarin should consider not taking CoQ10 because the risk of clotting may be increased. There is also evidence that environmental toxins deplete CoQ10.
A number of cardiac conditions can be treated with CoQ10. These include atherosclerosis, ischemic heart disease, aortic/mitral stenosis or insufficiency, diabetic cardiomyopathy, tetralogy of Fallot and atrial/ventricular septal defects. Other conditions where CoQ10 supplementation have proven helpful include congestive heart failure (CHF) angina, arrhythmias, mitral valve prolapse, and high blood pressure. CoQ10 has also been shown to be protective during cardiac surgery. Other disorders where CoQ10 has been used for successful treatment include diabetes, asthma, as well as AIDs, various cancers, ulcers, muscular disorders, immune system disorders and even aging!
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