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From Cells to Selves

From Cells to Selves

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The National Institute of Child Health and Human Development (NICHD) is setting forth its strategic ideas that will guide many, but not all, of its major research initiatives over the next several years. This plan is useful for Institute staff, the scientific community, and the public, all of whom have had a role in its preparation by providing a set of
priority research areas that will serve as the framework for Institute initiatives and enhanced funding.
Establishing such a strategic framework is a challenge for all Institutes, but is especially so for the NICHD due to the enormous diversity of its mission and to the areas of science that it actively pursues. But, it is an extremely important effort because so much of the health and well-being of the world’s population depends on the success of our
research. To us falls the task not of curing a single disease or group of diseases but of solving the fundamental question in biology and all that derives from it: how does a single fertilized egg develop into a fully functional adult human being, and how do a multitude of genetic and environmental factors influence that process for good or for ill. Thus the title of this plan: “From Cells to Selves.”
Solving this fundamental question is the key to the Institute achieving its mission: helping parents to have the children they want at the times they want them, helping every child be born healthy and every mother suffer no adverse consequences of the pregnancy, helping every child reach adulthood free of disease and disability and able to achieve his or her full potential; and ameliorating the consequences of physical or mental disability to enable all
individuals to function as fully as possible in society. To the extent that we succeed, we will solve many of the world’s most significant problems: ending unchecked population growth, minimizing mortality and morbidity of children, establishing a healthy physical and social environment, maximizing learning ability, preventing adult disease that
originates prenatally or in childhood, and developing healthy behavioral and social skills that are essential for success as well as for avoiding hostile interpersonal actions in a complex and diverse society.

The research efforts required to address these issues are as extensive and diverse as the scientific topics they encompass. These topics involve many disciplines, skills, and techniques, so that a “strategic framework” cannot possibly address them all. Consequently, this plan highlights some current areas for major emphasis due to their
importance and the emergence of scientific opportunities to address them. Future planning efforts will address additional areas
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