Blind Buddy and Mojo's Blues Band

From a dive in Memphis to Carnegie Hall, blues music has no permanent address. Guitarist and singer Blind Buddy O'Brian is fighting his way back to the top of the musical hill where he was before years of drugs and alcohol kept him in the low rent district. A new hit recording rising on the charts is overshadowed by the murder of his band's singer, Nina. The police tell Buddy he could be the next victim when they find he is being used as a drug mule each time his band goes on tour.

Buddy is side tracked by a cheating manager, a designing female police detective, and his own pride and arrogance. In spite of the best efforts of his girlfriend, Ivy, and his dog, Mojo, Buddy finds himself on the bad side of the blues.