The Autoimmune Diseases

The Autoimmune Diseases comprehensively describes the clinical expressions of all known autoimmune diseases, as well as the experimental bases of autoimmunity and failure of tolerance. The scientific chapters include mechanisms of natural tolerance, the genetic basis of autoimmunity, the significance of apoptosis, the influence of cytokines, environmental influences, and experimental models. The clinical chapters cover autoimmune endocrine deficiencies, insulin-dependent diabetes, rheumatic disorders, neurological diseases, and particular diseases of the blood, skin, eye, kidney, and liver. The 43 chapters are authored by worldwide authoritative contributors.

KEY FEATURES:
* provides comprehensive discussions of all autoimmune diseases and organ systems
* offers "bench to bedside" coverage of autoimmunity for both clinicians and scientists
* discusses the biologic basis of disease at genetic, molecular, cellular, and epidemiologic levels
* examines the environmental determinants of autoimmune disease
* examines the association between autoimmunity and aging, cancer, and AIDS