Precision Medicine and the Reinvention of Human Disease

Precision Medicine and the Reinvention of Human Disease clarifies the foundational concepts of precision medicine, distinguishing this field from its early predecessors, such as genomics, pharmacogenomics and personalized medicine. Until recently, most of medicine was focused on either the beginning or end-point of diseases. With precision medicine, attention has shifted to the precise steps of disease development. In particular, biomedical scientists are now looking for the key genetic and cellular pathways that lead to the emergence of a disease. Thus, precision medicine is reinventing disease in terms of events and pathways that will serve as targets for new preventive, diagnostic and therapeutic interventions.

This book discusses topics such as disease causality, genetics, diseases convergence and how to diagnose using precision medicine. Additionally, it is discussed the importance of data management and its impact on the future of this exciting field. It is a valuable source for bioinformaticians, computer biologists, geneticists and other members of the biomedical field who are interested in learning more about this new and very fundable field of precision medicine.

• Clarifies the foundational concepts of Precision Medicine, distinguishing this field from its predecessors such as genomics, pharmacogenetics, and personalized medicine.
• Gathers the chief conceptual advances in the fields of genetics, pathology, and bioinformatics, and synthesizes a coherent narrative for the field of Precision Medicine.
• Delivers its message in plain language, and in a relaxed, conversational writing style, making it easy to understand the complex subject matter.
• Guides the reader through a coherent and logical narrative, gradually providing expertise and skills along the way.
• Covers the importance of data sharing in Precision Medicine, and the many data-related challenges that confront this fragile new field.