Ischemia and Loss of Vascular Autoregulation in Ocular and Cerebral Diseases: A New Perspective

Ischemia and Loss of Vascular Autoregulation in Ocular and Cerebral Diseases: A New Perspective presents evidence that ischemia and loss of autoregulation of blood flow are associated with the onset of the major ocular and cerebral diseases including macular degeneration, diabetic retinopathy, low and normal tension open angle glaucoma, stroke and Alzheimer's disease. Recognition of these vascular changes underline the critical need for clinicians to monitor blood flow and autoregulation to improve early diagnosis and to optimize therapies of ocular and cerebral vascular diseases. The text brings to clinicians in Ophthalmology, Neurology, Medicine, Optometry and Geriatrics decisive guidance on the practical aspects for early diagnosis and treatment of ocular and cerebral diseases. The author brings together in a concise form the progress made over the span of his career and provides new perspectives and understanding of the fluid circulations of the eye and the brain. In addition, he explains the new analytical technologies that made the new concepts possible. The physiological and functional importance of blood flow autoregulation in the eye and in the brain in minimizing the progression of pathology, including the ischemia resulting from stenosis of the internal carotid artery and stroke, are also presented .