Bioinformatics: Sequence and Genome Analysis

The application of computational methods to DNA and protein science is a new and exciting development in biology. Bioinformatics: Sequence and Genome Analysis is a comprehensive introduction to this emerging field of study. The book has many unique and valuable features:

• It is written for any biologist who wants to understand methods of sequence and structure analysis and how the necessary computer programs work

• Sequence alignment, structure prediction, phylogenetic and gene prediction, database searching, and genome analysis are clearly explained and amply illustrated

• Underlying algorithms and assumptions are clearly explained for the non-specialist

• Examples are presented in simple numerical terms rather than complex formulas and notation

• Theoretical underpinnings are linked to biological problems and their solutions

• Extensive tables provide descriptions and Web sources for a broad range of publicly available software

Based on the author's extensive experience as a molecular geneticist and bioinformaticist at the University of Arizona, this is a uniquely educational book, ideal as a laboratory reference for investigators and also as teaching reference for graduate and undergraduate students studying this fast-changing discipline.