Epilepsy: Animal and Human Correlations

Correlation is a vital element in epilepsy research, especially given the condition's notorious resistance to treatment. With a current 'rate of translation' estimated at between seven and nine years, and a translation 'success rate' of below 50 per cent, there is room for improvement in the correlative research exploring this intractable condition. Epilepsy: Animal and Human Correlations offers judiciously selected material with clear correlative relevance. Arranged according to animal studies and related studies in the human population, each chapter covers clinical description, neurophysiology, neurochemistry, neuropathology, and treatment attempts. The human chapters have an additional section detailing studies based on counterpart animal studies, as well as covering promising further research suggested by animal results. The book includes a clear statement of the rationale for future human clinical investigations based on animal results. The chapters cover animal and human studies related to both simple and complex partial seizures. It covers typical as well as atypical seizures, and includes material on some seizure disorders which resist neat classification. Studies conducted in the primate population receive careful attention.