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ASM Press

Granulomatous Inflammations and Diseases: Cellular and Molecular Mechanisms

Granulomatous Inflammations and Diseases: Cellular and Molecular Mechanisms

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A comprehensive summary of knowledge on experimental and clinical granulomatoses.
• Covers the major aspects of the granulomatous response, providing the basis for the understanding of the overall granulomatous immune response and its resolution.
• Provides an in-depth discussion of the mechanistic basis of inflammation in a number of representative granulomatous diseases, illustrates different cellular responses and immune mechanisms within the framework of the general granulomatous response.
• Examines experimental treatments of mice by cell transfer between donor and recipient, infection of inflammatory/regulatory cytokines or cytokine-neutralizing antibodies, and use of mice genetically deficient in cytokine/chemokine production or cytokine/chemokine receptor expression.
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