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ASM Press
Pathogenesis of Human Pulmonary Tuberculosis: Insights from the Rabbit Model
Pathogenesis of Human Pulmonary Tuberculosis: Insights from the Rabbit Model
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Examines the pathogenesis of human pulmonary tuberculosis in all of its stages, with a primary focus on the rabbit model.
• Reviews the interplay of delayed-type hypersensitivity and cell-mediated immunity, clearly showing how both are needed to control the growth of the tubercle bacillus and how antibodies contribute to these cellular immune responses.
• Covers the histochemistry of macrophage activation; the roles of various cytokines; the effects of glucocorticoids, estrogens, thyroid hormones, and irradiation on the disease; and principles of immunization against tuberculosis, including vaccine development.
• Focuses on areas of future research that could contribute to the knowledge, treatment, and control of this disease.
• Serves as a resource for clinicians, public health investigators, and laboratory researchers in tuberculosis and immunology.
• Reviews the interplay of delayed-type hypersensitivity and cell-mediated immunity, clearly showing how both are needed to control the growth of the tubercle bacillus and how antibodies contribute to these cellular immune responses.
• Covers the histochemistry of macrophage activation; the roles of various cytokines; the effects of glucocorticoids, estrogens, thyroid hormones, and irradiation on the disease; and principles of immunization against tuberculosis, including vaccine development.
• Focuses on areas of future research that could contribute to the knowledge, treatment, and control of this disease.
• Serves as a resource for clinicians, public health investigators, and laboratory researchers in tuberculosis and immunology.
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