Drug Discovery and Design: Medical Aspects

Essentially a continuation of volume 22 in the series, the 36 review and research articles cover the synthesis and properties of bioactive molecules and enzymes, the role of membranes in drug activity and formulation, the conformational analysis of bioactive compounds, and molecular targets and drug designs. Most of them were written by Greek specialists as part of a lecture series in the course Medicinal Chemistry for graduate students. A sampling of topics turns up the growth inhibitory and apoptotic effects of gonadotropin-releasing hormone on human hepatocellular carcinoma, and using synthetic peptides to identify biologically active domains of the growth factor HARP. There is no subject index. Annotation ©2004 Book News, Inc., Portland, OR