Toxicogenomics and Proteomics

Toxicology uses a variety of models to assess the behavioral and histopathological consequences of exposure to certain chemicals, primarily those described here as "environmental insults." While useful to some degree, these assessments are not particularly helpful in determining the outcome of low-level exposure, or exposure to several chemicals, and they do not offer sufficient explanations of outcomes on the molecular level. In this collection of 15 papers, contributors describe research in new studies of gene activity which make it possible to develop a predictive toxicology based on analyses of the genome, proteome, and metabolome. The collection includes papers on classic toxicology as well as the new fields of research. Also, because developing nations tend to have the toxicological problems while developed nations tend to have the latest technological developments, the collection includes papers addressing toxicology in public health research. Annotation ©2004 Book News, Inc., Portland, OR