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Cold Spring Harbor Laboratory Press

Translation Mechanisms and Control

Translation Mechanisms and Control

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Translation converts the genetic code in messenger RNA molecules copied from DNA into a specific sequence of amino acids in a protein. It occurs on ribosomes in the cell cytoplasm and is one of the most fundamental biological processes. This volume examines the detailed molecular machinery responsible for translation and the regulatory mechanisms that make the process a critical control point for the cell.

Topics covered in this essential volume include:
- History of Protein Synthesis and Translational Control
- Protein Synthesis Initiation in Eukaryotic Cells
- Translation in Prokaryotes
- New Insights into Ribosome Structure and Function
- Translational Control in Virus-Infected Cells
- Translating Therapeutics

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