Genome Mapping and Sequencing

Acknowledged experts in the field of DNA sequencing and mapping describe in detail the latest innovations in this vital area of science. The newest technology and procedures in areas such as radiation hybrid mapping, construction of libraries, YACs, FISH, assembly of physical maps, shotgun sequencing and specialized sequencing techniques are all fully covered. There is a particular emphasis on the whole chromosome approach to mapping and sequencing. In addition, several chapters cover genomic sequencing software and sequence databases. Eminent international scientists describe the technology necessary to map and sequence the entire genome in a holistic manner and the high throughput and large-scale experimental methodologies currently available. This book is an essential volume for everyone involved in DNA sequencing and mapping.