Papillomavirus Research: From Natural History to Vaccines and Beyond

Papillomaviruses are oncogenic DNA tumor viruses that infect humans and animals. Human papillomavirus is one of the most common causes of sexually transmitted infection in the world and can also cause cancer. Papillomavirus research has been revolutionized in recent years with the advent of new technologies such as organotypic raft cultures, virus-like particles, and transgenic mice. New facets of virion structure, life cycle, immunology, and oncogenicity have recently emerged. In this timely book, leading scientists review current aspect of papillomavirus research providing a fascinating insight into papillomavirus molecular biology, interactions with the host, immunology, and vaccine development. Topics covered include epidemiology and taxonomy, phylogenetic analysis, gene expression, regulation of DNA replication, transcription factor proteins, organotypic raft cultures, virus-like particles, and much more. Essential reading for scientists and researchers working on papillomavirus and a recommended text for anyone involved with antiviral drug and vaccine development.