Snake Venom Metalloproteinases

This special edition of Toxins will cover recent developments in snake venom metalloproteinase structure, function and clinical implications. It will include a historical retrospective of the discovery of Snake Venom Metalloproteinases (SVMPs) and early insights into their biochemical mechanisms and how they function in envenomation. The individual articles will review

• SVMP Structure

• Pathologies associated with SVMPs activities

• Mechanism of action; evolution and orthologs

• SVMP processing and disintegrins

• Potential clinical applications of SVMP scaffolds