Bitot's Spots

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Bitot's spots are the buildup of keratin debris located superficially in the conjunctiva, which are oval, triangular or irregular in shape. These spots are a sign of vitamin A deficiency and are associated with conjunctival xerosis. In 1863 Bitot, a French physician, first described these spots. In ancient Egypt, this was treated with animal liver. Keratin refers to a family of fibrous structural proteins. Keratin is the key of structural material making up the outer layer of human skin. It is also the key structural component of hair and nails.